Publications by authors named "M R Blichfeldt-Eckhardt"
Article Synopsis
- The study aimed to improve the prediction of outcomes after total hip arthroplasty (THA) by examining the role of inflammatory biomarkers in blood and cerebrospinal fluid (CSF) related to osteoarthritis and pain.
- Researchers analyzed data from 50 patients, assessing changes in pain and disability 12 months post-surgery, while considering factors like age, sex, and BMI.
- Results showed that preoperative systemic inflammation in blood was linked to better postoperative outcomes, while neuroinflammation was tied to preexisting pain, suggesting that inflammatory biomarkers could help select patients for THA more effectively in the future.
Pain profiles and variability in temporal summation of pain and conditioned pain modulation in pain-free individuals and patients with low back pain, osteoarthritis, and fibromyalgia.
Eur J Pain
October 2024
Article Synopsis
- The study investigates the variability of pain profiles, specifically temporal summation of pain (TSP) and conditioned pain modulation (CPM), among patients with chronic musculoskeletal pain and compares them to pain-free individuals.
- It identifies distinct pain profiles based on TSP and CPM levels and finds high TSP and low CPM most prevalent in fibromyalgia and osteoarthritis patients.
- Despite the differences in pain profiles, there were no significant correlations found between these profiles and the intensity of clinical pain experienced by patients.
Objectives: Chronic pain poses a significant health challenge worldwide and is associated with both disability and reduced quality of life. Sleep disturbances are reported in 67% to 88% of patients with chronic pain. Pain and sleep affect each other reciprocally; we aimed to study this bidirectional relationship in patients treated with spinal cord stimulation (SCS) for chronic pain.
View Article and Find Full Text PDFPurpose: Increasing recognition of chronic pain diseases, including Fibromyalgia, warrants the need for tools to monitor the impact of the disease as well as the efficacy of interventions. The Revised Fibromyalgia Impact Questionnaire (FIQR) has previously proved to be a valuable tool in both clinical and research settings. The study objective was to translate and validate the FIQR in Danish.
View Article and Find Full Text PDFExamining the Duration of Carryover Effect in Patients With Chronic Pain Treated With Spinal Cord Stimulation (EChO Study): An Open, Interventional, Investigator-Initiated, International Multicenter Study.
Neuromodulation
July 2024
Article Synopsis
- Spinal cord stimulation (SCS) is a surgical method used to treat severe chronic neuropathic pain and is thought to have a carryover effect, where pain perception is delayed after the device is turned off.
- An international study was conducted with 158 eligible patients to systematically measure the carryover time, defined as the duration between deactivation and reactivation of the SCS device.
- The findings revealed a median carryover time of five hours, with various factors like the type of pain and stimulation influencing the length of this carryover time.