Publications by authors named "M R Bergen"

For end-stage renal disease (ESRD) patients requiring hemodialysis, reliable vascular access is crucial, especially when conventional supradiaphragmatic options are exhausted. This study reviews the technical aspects, clinical outcomes, and complications of translumbar and transhepatic tunneled dialysis catheter (TDC) placements. These alternative infradiaphragmatic approaches provide essential hemodialysis access for patients with central venous occlusions.

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Background: While acute compartment syndrome (ACS) is a well-reported complication after pediatric tibial shaft fractures, prior literature has suggested that pediatric patients with tibial tubercle fractures may be at increased risk of ACS due to the proximity of the tibial tubercle to the anterior tibial recurrent artery. However, this theory was largely based on a series of early case reports without substantiation in larger-scale studies.

Hypothesis/purpose: The purpose of this study is to conduct a population-level analysis of the incidence and risk factors of acute compartment syndrome following pediatric tibial tubercle and tibial shaft fractures.

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Article Synopsis
  • Multi-omics data integration is a key focus in toxicology for better understanding cellular responses to chemical exposure; the study reviews current practices and provides guidelines for optimal multi-omics research design.
  • Despite recognizing the benefits, the researchers found limited availability of comprehensive multi-omics datasets, hindering a full evaluation of the methodologies used in toxicology.
  • In their own study on thyroid toxicity, they utilized a multi-omics approach to identify regulatory responses and discovered that integrating multiple omics layers enhances data interpretation and reveals insights into mechanisms like non-coding RNA involvement.
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