Unsymmetrical Imidazopyrimidine-Based Ligand and Bimetallic Complexes.

With bimetallic catalysts becoming increasingly important, the development of electronically and structurally diverse binucleating ligands is desired. This work describes the synthesis of unsymmetric ligand 2,7-di(pyridin-2-yl)imidazo[1,2-]pyrimidine () that is achieved in four steps on a multigram scale in an overall 54% yield. The ability of to act as a scaffold for the formation of bimetallic complexes is demonstrated with the one-step syntheses of the dicopper complex [Cu()(μ-OH)(CFCOO)] (), the dipalladium complex [Pd()(μ-OH)(CFCOO)](CFCOO)·CFCOOH (), and the dimeric dinickel complex [Ni()(μ-Cl)ClMeOH][2Cl] () in good yields (79-92%).

[Chronic persistent infections of anterior segment of eye: clinico-laboratory aspects].

Aim: Improvement of therapy of chronic ophthalmic infectious diseases during assessment of functioning of different arms of immune system.

Materials And Methods: Three hundred and fifty patients with chronic red-eye syndrome were tested by immunofluorescence assay on the presence of antigens of herpesviruses, adenoviruses and Chlamydia in samples from conjunctiva. Expression of 11 cytokines' genes was measured in peripheral blood mononuclear cells by reverse transcription polymerase chain reaction.

[The antirelapse effectiveness of amyxin used in combination with antiherpetic vaccine in patients with herpetic keratitis].

The efficiency of the combined use of amixin and anti-herpetic vaccination (AHV) to prevent the relapses of herpetic keratitis (HK) is investigated. One hundred and four patients with HK were followed up. The efficiency was found to be higher in the group of patients who received both amixin and AHV: in 29 (87.