Cerebral spinal fluid analyses and therapeutic implications for leptomeningeal metastatic disease.

Purpose: To review applications of cerebral spinal fluid (CSF) biomarkers for the diagnosis, monitoring and treatment of leptomeningeal metastatic disease (LMD) among patients with metastatic solid tumors.

Methods: A narrative review identified original research related to CSF biomarkers among patients with metastatic solid tumors and LMD. Pre-clinical research (e.

Heavy metals concentration and human health risk assessment in selected shrimp species of Pakistan.

Heavy metal pollution in marine organisms poses a significant threat to both ecosystems and human health. Dumping untreated sewage into the sea pollutes coastal waters with toxic metals. This study examined the levels of chromium (Cr), lead (Pb), nickel (Ni), mercury (Hg), arsenic (As) and copper (Cu) in three shrimp species of genus i.

Living biodrugs and how tissue source influences mesenchymal stem cell therapeutics for heart failure.

In this editorial we comment on the article by Safwan M . We especially focused on the cardiac function restoration by the use of mesenchymal stem cells (MSCs) therapy for heart failure (HF), which has emerged as a new treatment approach as "Living Biodrugs". HF remains a significant clinical challenge due to the heart's inability to pump blood effectively, despite advancements in medical and device-based therapies.