Publications by authors named "M QUIJANO"
Article Synopsis
- Chagas disease (CD) is a growing global health concern, particularly among Latin American migrants in non-endemic countries, prompting a systematic review to determine its prevalence in this population.* -
- Out of 1474 articles screened, 51 studies were included, indicating a pooled CD prevalence of 3.5% among Latin American migrants, with higher rates in specific subgroups such as unselected populations (11.0%) and pregnant women (3.7%).* -
- The research highlights the importance of screening among Latin American migrants and reveals significant levels of congenital transmission at 4.4%, emphasizing the need for public health strategies in non-endemic regions.*
Article Synopsis
- - The study aimed to update the understanding of the prevalence of clinical forms of Chagas disease (ChD) among seropositive adults by pooling data from various studies published from 1990 to August 2023.
- - A systematic review included 73 studies with over 17,000 patients, finding that the estimated prevalence was 42.6% for the indeterminate form, 42.7% for chronic Chagas cardiomyopathy (CCM), 17.7% for digestive forms, and 10.2% for mixed forms.
- - The research highlighted a higher prevalence of CCM compared to earlier reports, while the prevalence of digestive forms remained consistent, and showed that older age correlates with higher figures
Chagas disease (ChD), a Neglected Tropical Disease, has witnessed a transformative epidemiological landscape characterized by a trend of reduction in prevalence, shifting modes of transmission, urbanization, and globalization. Historically a vector-borne disease in rural areas of Latin America, effective control measures have reduced the incidence in many countries, leading to a demographic shift where most affected individuals are now adults. However, challenges persist in regions like the Gran Chaco, and emerging oral transmission in the Amazon basin adds complexity.
View Article and Find Full Text PDFBackground: Chagas disease (CD) is a neglected disease affecting millions worldwide, yet little is known about its economic burden. This systematic review is part of RAISE project, a broader study that aims to estimate the global prevalence, mortality, and health and economic burden attributable to chronic CD and Chronic Chagas cardiomyopathy. The objective of this study was to assess the main costs associated with the treatment of CD in both endemic and non-endemic countries.
View Article and Find Full Text PDFConsumer products containing botanicals or natural substances (BNS) are often preferred because there is a perception that 'natural' is safe. As with any product ingredient, a thorough safety assessment must be conducted, including a determination of skin sensitization potential. A modification of the Peroxidase Peptide Reactivity Assay (PPRA) was explored for screening BNS (B-PPRA) for their reactivity to a model cysteine peptide.
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