Publications by authors named "M Prust"

Article Synopsis
  • Neurocritical illnesses often lead to increased mortality in low-resource countries, and early neurodeterioration (END) may help identify high-risk patients for better care.
  • A study conducted in Zambia monitored neurology inpatients to assess the impact of END, defined as a decline in the Glasgow Coma Scale (GCS) within three days of admission.
  • The results showed that 18% of patients experienced END, significantly increasing their risk of death (72% vs 11% mortality), with common causes of death being aspiration pneumonia and sepsis, indicating a need for targeted interventions.
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Background: To make the best use of health resources, it is crucial to understand the healthcare needs of a population-including how needs will evolve and respond to changing epidemiological context and patient behaviour-and how this compares to the capabilities to deliver healthcare with the existing workforce. Existing approaches to planning either rely on using observed healthcare demand from a fixed historical period or using models to estimate healthcare needs within a narrow domain (e.g.

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Neurologic diseases represent a significant global health challenge, leading to disability and mortality worldwide. Healthcare systems in low- and middle-income countries are disproportionally affected. In these resource-limited settings, numerous barriers hinder the effective delivery of emergency and inpatient neurologic care, including shortages of trained personnel, limited access to diagnostics and essential medications, inadequate facilities, and absence of rehabilitation services.

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Stroke is the second leading cause of death and the third leading cause of disability worldwide. Though the burden of stroke worldwide seems to have declined in the past three decades, much of this effect reflects decreases in high-income countries (HICs). By contrast, the burden of stroke has grown rapidly in low-income and middle-income countries (LMICs), where epidemiological, socioeconomic and demographic shifts have increased the incidence of stroke and other non-communicable diseases.

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