Publications by authors named "M Procaccini"
Introduction: Despite new anti-seizure medications (ASMs) being introduced into clinical practice, about one-third of people with epilepsy do not reach seizure control. Cenobamate is a novel tetrazole-derived carbamate compound with a dual mechanism of action. In randomized controlled trials, adjunctive cenobamate reduced the frequency of focal seizures in people with uncontrolled epilepsy.
View Article and Find Full Text PDFUsing insulin pump for glycemic control in patients with severe insulin resistance.
J Am Pharm Assoc (2003)
March 2024
Background: Patients with type 2 diabetes using a continuous subcutaneous insulin infusion (CSII) often require large doses of insulin and need to change their insulin administration sets frequently. A proposed solution to this problem is to use concentrated insulin in their insulin pump; however, insulin pumps are programmed to administer U-100 insulin. Therefore, these patients are at greater risk of hypoglycemia and are responsible for adjusting daily doses.
View Article and Find Full Text PDFArticle Synopsis
- The study examined opioid prescriptions and utilization in pediatric orthopaedic surgery patients amidst the opioid epidemic, finding that many children do not use their entire prescription.
- Data was gathered from 280 patients, with 102 providing detailed utilization information, revealing that over half of prescribed patients used no opioids post-surgery and 96.2% used them for five days or less.
- Results indicated that children with upper extremity fractures received fewer opioids and that higher body mass index correlated with increased opioid prescriptions, highlighting the need for careful prescription practices.
Processing large-scale graphs is challenging due to the nature of the computation that causes irregular memory access patterns. Managing such irregular accesses may cause significant performance degradation on both CPUs and GPUs. Thus, recent research trends propose graph processing acceleration with Field-Programmable Gate Arrays (FPGA).
View Article and Find Full Text PDFAnalysis of Patients with Focal Epilepsy and Drug-Resistant Epilepsy in Italy: Evaluation of Their Characteristics, Therapeutic Pathway and the Consumption of Healthcare Resources.
Clinicoecon Outcomes Res
July 2022
Purpose: A retrospective analysis was conducted to estimate the number of patients with focal epilepsy and drug-resistant epilepsy (DRE) and their characteristics, the therapeutic patterns, the consumption of health resources in a real-world Italian setting.
Patients And Methods: A retrospective study was carried out on the administrative databases of a sample of Italian Health Departments, covering approximately 8.7 million health-assisted individuals.