Introduction: Good hand hygiene compliance among healthcare workers is crucial for preventing healthcare-associated infections. While an extensive amount of research has focused on barriers to compliance with hand hygiene guidelines, there remains a critical gap in understanding the factors contributing to consistently excellent compliance among some individuals. Thus, the main aim of this study is to learn from these "champions" of hand hygiene and identify facilitating factors that enable and sustain high compliance using the Theoretical Domains Framework (TDF).
View Article and Find Full Text PDFOptimal multi-layer device design requires consideration of fabrication uncertainties associated with inter-layer alignment and conformal layering. We present layer-restricted topology optimization (TO), which we believe to be a novel technique which mitigates the effects of unwanted conformal layering for multi-layer structures and enables TO in multi-etch material platforms. We explore several approaches to achieve this result compatible with density-based TO projection techniques and geometric constraints.
View Article and Find Full Text PDFEmerg Med Clin North Am
February 2025
The balance between risk of missing serious disease and potential harms from over testing involves knowledge of the literature, familiarity of clinical guidelines, incorporation of clinical decision tools where appropriate, use of metacognition to be aware of cognitive decisions to respond and use of shared decision-making in the context of a patient's presentation and with the guidance of the clinician.
View Article and Find Full Text PDFThe reaction mechanisms and corresponding structure-activity relationships of tertiary amines with respect to CO capture have been investigated using density functional theory (DFT) calculations. The reaction mechanism for CO capture via base-catalyzed hydration to form bicarbonate is proposed to proceed in a single step involving proton transfer and the formation of a carbon-oxygen bond. Based on the height of the reaction barriers, we suggest that amines containing side chains with the ethyl group, along with a single hydroxyl group, and cyclic structures, are especially active for CO capture.
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