Publications by authors named "M Priesca-Marin"
Self-reported changes in the expanded disability status scale score in patients with multiple sclerosis after autologous stem cell transplants: real-world data from a single center.
Clin Exp Immunol
December 2019
Article Synopsis
- Autologous hematopoietic stem cell transplantation (HSCT) was performed on 617 MS patients to reset their immune systems, involving outpatient procedures with cyclophosphamide and rituximab conditioning.
- A total of 401 females and 216 males, with a median age of 46, participated, including various types of MS: 259 with relapsing-remitting, 228 with secondary progressive, and 130 with primary progressive.
- The study showed a 100% overall survival rate after 30 months, with 78% of patients experiencing improvement or stabilization in their disability status after 12 months.
A Feasibility Study of the Full Outpatient Conduction of Hematopoietic Transplants in Persons with Multiple Sclerosis Employing Autologous Non-Cryopreserved Peripheral Blood Stem Cells.
Acta Haematol
July 2017
Background: With the goal of achieving immune system reset, autologous hematopoietic stem cell transplantations have been performed in patients with multiple sclerosis (MS).
Material And Methods: Two hundred and eighty-six consecutive patients with MS were autografted in a single center using non-frozen peripheral blood stem cells (PBSCs), on an outpatient basis and conditioning with cyclophosphamide and rituximab. The protocol was registered in ClinicalTrials.
A single apheresis procedure in the donor may be enough to complete an allograft using the "Mexican method" of non-ablative allografting.
Blood Transfus
April 2009
Background: Since 1999, in Mexico we have been using a regimen to conduct allografts that involves non-myeloablative conditioning and peripheral blood stem cells (PBSC) and have introduced some changes with the main goal of decreasing the cost of the procedure.
Materials And Methods: We analysed the salient apheresis features of a group of 175 allogeneic peripheral blood stem cell transplants conducted in two institutions in a 7-year period. The grafts were conducted using the "Mexican" non-myelo ablative conditioning regimen employing oral busulphan, i.