Transformative nanobioplasmonic effects: Toxicological implications of plasmonic silver nanoparticles in aquatic biological models.

Silver nanoparticles (AgNPs) present unique properties, such as the induced localized surface plasmon resonance (LSPR) provoked under illumination with a proper wavelength, allowing these nanomaterials to be applied in fields such as catalysis and biomedicine. The study of AgNPs is also highly relevant from the environmental pollution viewpoint due to their high production and application in commercial products. Consequently, AgNPs reach aquatic environments and can be plasmonically stimulated under natural light conditions.

Biotic homogenization in multisystem cascade reservoirs: insights from sedimentary photopigment analysis.

The existing literature provides limited insights into the dynamics of phytoplankton communities and the spatial heterogeneity of physicochemical parameters in multisystem cascade reservoirs (interconnected reservoirs derived from different rivers). The existing studies are concentrated on cascade reservoirs (interconnected reservoirs derived from the same river). To address this knowledge gap, the aims of the present study were as follows: (1) investigate the spatial heterogeneity, within and between reservoirs, of geochemical parameters associated with the eutrophication process, considering total phosphorus, chlorophyll-a, pheophytin, and metals (chromium, copper, nickel, lead, zinc, iron, and manganese); (2) evaluate sediment quality at the designated locations; (3) assess differences in the richness and concentration of sedimentary photopigments between the reservoirs.

More than just sweet: current insights into microplastics in honey products and a case study of honey.

Honey, traditionally known as a pure and natural substance, has become an unexpected reservoir for microplastic contamination. This study consisted of an experimental investigation to assess the occurrence of microplastics in honey produced by , a native bee species in Brazil. Our investigation covers eight areas (one sample per area), including built and vegetated areas located in São Paulo city, Brazil, to understand the distribution of microplastics in these environments.

Umpolung Flow Chemistry for the Synthesis of a 3-Oxo-3-spiro[benzofuran-2,4'-piperidine] Building Block.

An efficient and scalable route to -butyl 3-oxo-3-spiro[benzofuran-2,4'-piperidine]-1'-carboxylate, a central prochiral intermediate in the synthesis of SHP2 inhibitor (), was achieved. Preparation of the title compound from readily available 2-fluorobenzaldehyde included formation of a modified Katritzky benzotriazole hemiaminal, which, upon deprotonation by -butyllithium, participated in umpolung reactivity via 1,2-addition to -butyl 4-oxopiperidine-1-carboxylate (-Boc-4-piperidone). Most notably, this reaction was developed as a robust plug-flow process that could be executed on multiple kilograms without the need for pilot-scale reaction vessels operating at low cryogenic temperatures.