Publications by authors named "M Pisaturo"
Article Synopsis
- - The study aimed to evaluate the rate of false-positive cases for congenital heart defects (CHDs) during first-trimester fetal heart evaluations conducted by experienced professionals.
- - It looked at a group of pregnant women suspected of having CHDs during initial screenings, utilizing comprehensive protocols that included critical heart assessment views.
- - Among the 22 cases analyzed, a high percentage (86.4%) were confirmed to have CHDs, but 13% showed normal heart anatomy, indicating that first-trimester screenings may lead to more false positives than anticipated.
Background: Tuberculosis (TB) remains a Global Health challenge, with diagnostic delays contributing significantly to its spread. This study investigates the differences in diagnostic delays between native and migrant TB patients in Italy, examining patient-related diagnostic delay (PDD), health system-related diagnostic delay (HDD), and total diagnostic delay (TDD).
Methods: We conducted a retrospective, multicenter, cross-sectional study of TB cases in 10 Italian hospitals from 2018 to 2023.
Article Synopsis
- The meta-analysis aimed to compare the efficacy and safety of two-drug regimens versus triple-drug regimens in virosuppressed people living with HIV (PLWH) over a 96-week follow-up period.
- The review included six studies, assessing treatment failure, virological failure, adverse drug reactions, and mutations, with no significant differences found between the two treatment approaches.
- The findings support the use of two-drug regimens as a simpler and effective treatment option for improving clinical outcomes in virosuppressed PLWH.
Article Synopsis
- - Infections caused by multidrug-resistant organisms (MDRO) pose significant public health risks due to high rates of illness and death, particularly concerning Gram-positive bacteria.
- - A comprehensive review was conducted to explore current treatment options for Gram-positive MDROs, highlighting the ongoing relevance of glycopeptides, which have been the standard treatment for over 70 years.
- - Research is also focusing on non-traditional antibacterial agents, suggesting that these newer treatments should complement rather than replace traditional antibiotics to enhance effectiveness and patient outcomes.
Background: Migrants, mainly undocumented and low-income refugees, are at high risk of hepatitis C virus (HCV) infection, but are a difficult-to-reach and to-treat population. The aim of the study was to evaluate the effectiveness of a test and treat model with direct-acting antiviral for HCV infection in these migrants coming from low-income and living in southern Italy.
Methods: A prospective, multicenter, collaborative study based on a four-phase-program (educational counseling, screening, linkage-to-care and treatment) was designed in southern Italy; the study started in June 2018, was stopped in February 2020 because of the outbreak of SARS-CoV2 infection in Italy and was resumed in February 2021 until November 2021.