Publications by authors named "M Piqueras"
Introduction: Crohn's disease (CD) varies by location, potentially affecting therapy efficacy and surgery risk, although research on this topic is conflicting. This study aims to investigate the independent association between CD location and therapeutic patterns.
Methods: We analyzed patients with CD diagnosed from January 2005 to May 2023 registered in the nationwide ENEIDA registry.
Article Synopsis
- Complications from community-acquired pneumonia (CAP), such as cardiovascular events and mortality, can arise both during the illness and afterward; this study explores the role of specific biomarkers related to endothelial damage compared to traditional inflammation markers.
- The research analyzed data from 515 patients, measuring various biomarkers at different time intervals (day 1, day 5, and day 30) to determine their relationship with ICU admission, cardiovascular events, and mortality.
- Findings indicated that endothelial damage biomarkers (CT-proET-1 and MR-proADM) were more strongly associated with negative outcomes than inflammation markers (CRP and PCT), with MR-proADM being the most effective at predicting complications in both the short and long term.
Background And Aims: Inflammatory pouch disorders exhibit a heterogeneous clinical spectrum and therapeutic requirements have not been properly studied.
Methods: This retrospective, multicentre study included ulcerative colitis patients with ileal pouch construction and were later diagnosed with an inflammatory pouch disorder between 1995 and 2020. Classifications, behaviour and therapies applied were recorded and compared in the long-term.
Immunohistochemical studies have identified complement component C1q in MS lesions. We aimed to compare serum (sC1q) and CSF (csfC1q) levels in a large cohort of MS patients (pwMS) (n = 222) with those of healthy controls (HC, n = 52), individuals with other immune (IND, n = 14), and non-immune neurological disorders (nIND, n = 15), and to analyze their correlation with other biomarkers. pwMS were divided into three series based on their origin.
View Article and Find Full Text PDFBackground: Ulcerative proctitis (UP) can have a milder, less aggressive course than left-sided colitis or extensive colitis. Therefore, immunosuppressants tend to be used less in patients with this condition. Evidence, however, is scarce because these patients are excluded from randomised controlled clinical trials.
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