Publications by authors named "M Pink"
The synthesis and isolation of TerP═GaTer and TerP═InTer (Ter = 2,6-Dipp-CH; Dipp = 2,6-diisopropylphenyl) is reported. These compounds feature unsupported P═Ga and P═In double bonds and two-coordinate triel element centers. Key to the stabilization of such compounds is the steric bulk of the terphenyl substituents, which serve to shield the highly reactive P═E bonds (E = Ga, In) and prevent further aggregation.
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- Researchers developed new cisplatin-like platinum metalloenediynes using thermally resistant phosphine enediyne ligands, demonstrating how different ligand substituents affect cyclization kinetics.
- The first crystallographic studies of these complexes revealed they have short inter alkyne distances, indicating a potential for spontaneous cyclization at room temperature, influenced by their electronic properties.
- Kinetic studies showed that complexes with electron-donating groups cyclized much faster than those with electron-withdrawing groups due to their unique electronic effects on bond formation and cyclization barriers.
Aim(s): This study reports on the implementation of a registered advanced nurse practitioner intervention. Aims include improving access, service user outcomes and integration between primary and secondary care.
Design: This paper reports the quantitative results of a mixed methods implementation study.
Despite their potential relevance as molecular models for industrial and biological catalysis, well-defined mononuclear iron carbide complexes are unknown, in part due to the limited number of appropriate C synthons. Here, we show the ability of the cyaphide anion (C≡P) to serve as a C source. The high spin ( = 2) cyaphide complex PhB(BuIm)Fe-C≡P (PhB(BuIm) = phenyl(tris(3--butylimidazol-2-ylidene)borate) is readily accessed using the new cyaphide transfer reagent [Mg(NacNac)(CP)] (NacNac = CH{C(CH)N(Dipp)} and Dipp = 2,6-di(iso-propyl)phenyl).
View Article and Find Full Text PDFProteomic investigations result in high dimensional datasets, but integration or comparison of different studies is hampered by high variances due to different experimental setups. In addition, cell culture conditions can have a huge impact on the outcome. This study systematically investigates the impact of experimental parameters on the proteomic profiles of commonly used cell lines-A549, differentiated THP-1 macrophage-like cells, and NR8383-for toxicity studies.
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