Publications by authors named "M Pietila"
Myocardial bridging (MB) is a common anatomic variant in coronary arteries with unclear functional significance. We evaluated regional myocardial strain by speckle tracking during dobutamine stress echocardiography (DSE) in patients with MB in the left anterior descending coronary artery (LAD). We studied 11 patients with MB in the LAD and no obstructive coronary artery disease (CAD), 7 patients without MB, but obstructive CAD in the LAD, and 12 controls without MB or obstructive CAD.
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- Semaglutide, a GLP-1 receptor agonist used for weight loss, may lower the risk of serious cardiovascular issues in individuals with obesity, but its specific effects on those with pre-existing heart conditions, like atherosclerotic cardiovascular disease and heart failure, were unclear.
- The SELECT trial, a comprehensive study involving adult participants with cardiovascular disease and high BMI, examined the impact of weekly injections of semaglutide versus placebo on heart-related outcomes, particularly focusing on those with varying types of heart failure.
- Researchers looked for differences in cardiovascular events, analyzing data to see if treatment efficacy and safety were affected by heart failure type and participants’ initial health characteristics.
Background Coronary artery calcium (CAC) has prognostic value for major adverse cardiovascular events (MACE) in asymptomatic individuals, whereas its role in symptomatic patients is less clear. Purpose To assess the prognostic value of CAC scoring for MACE in participants with stable chest pain initially referred for invasive coronary angiography (ICA). Materials and Methods This prespecified subgroup analysis from the Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease (DISCHARGE) trial, conducted between October 2015 and April 2019 across 26 centers in 16 countries, focused on adult patients with stable chest pain referred for ICA.
View Article and Find Full Text PDFImportance: The effectiveness and safety of computed tomography (CT) and invasive coronary angiography (ICA) in different age groups is unknown.
Objective: To determine the association of age with outcomes of CT and ICA in patients with stable chest pain.
Design, Setting, And Participants: The assessor-blinded Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease (DISCHARGE) randomized clinical trial was conducted between October 2015 and April 2019 in 26 European centers.