Resistance to bacteriophage incurs a cost to virulence in drug-resistant .

is a critical priority pathogen for novel antimicrobials (World Health Organization) because of the rise in nosocomial infections and its ability to evolve resistance to last resort antibiotics. is thus a priority target for phage therapeutics. Two strains of a novel, virulent bacteriophage (LemonAid and Tonic) able to infect carbapenem-resistant (strain NCTC 13420), were isolated from environmental water samples collected through a citizen science programme.

Developing the CARE intervention to enhance ethical self-efficacy in dementia care through the use of literary texts.

Background: Dementia care is essential to promote the well-being of patients but remains a difficult task prone to ethical issues. These issues include questions like whether manipulating a person with dementia is ethically permissible if it promotes her best interest or how to engage with a person who is unwilling to recognize that she has dementia. To help people living with dementia and their carers manage ethical issues in dementia care, we developed the CARE intervention.

Cognitive-behavioural reflective training for improving critical thinking disposition of nursing students.

Background/objective: The importance of critical thinking in improving treatment practices in, for instance, the nursing profession, cannot be overemphasized. Despite this importance, empirical studies have shown that helping strategies to train learners on critical thinking disposition are needed. Given this knowledge gap, this study investigated the impacts of cognitive-behavioral reflective training for improving the critical thinking disposition of nursing students.

Na-MRI as a Noninvasive Biomarker for Cancer Diagnosis and Prognosis.

The influx of sodium (Na ) ions into a resting cell is regulated by Na channels and by Na /H and Na /Ca exchangers, whereas Na ion efflux is mediated by the activity of Na /K -ATPase to maintain a high transmembrane Na ion gradient. Dysfunction of this system leads to changes in the intracellular sodium concentration that promotes cancer metastasis by mediating invasion and migration. In addition, the accumulation of extracellular Na ions in cancer due to inflammation contributes to tumor immunogenicity.

Physician Training Ultrasound and Accuracy of Diagnosis in Rotator Cuff Tears.

Introduction: Ultrasonography offers a fast and inexpensive method to evaluate the rotator cuff in the office setting. However, the accuracy of ultrasound is highly user dependent. The purpose of this study is to investigate the learning curve of an orthopaedic surgeon in using ultrasound to diagnose rotator cuff tears.