Comparison of twice- and three times daily tiagabine for the adjunctive treatment of partial seizures in refractory patients with epilepsy: an open label, randomised, parallel-group study.

Unlabelled: A multicentre, open label, randomised, parallel group study compared the efficacy, tolerability and safety of two dosing regimens, t.i.d.

Symptomatology and prognosis in adolescent epilepsies (a study of 1033 cases).

A follow-up study was carried out on a group of 1033 epilepsy patients seen consecutively between 1955 and 1979. They were all aged between 11 and 19 years at the time of first seizure. Nine hundred and twelve patients were followed up for periods of 5-30 years.

[Discontinuation of treatment in epileptic seizures in adolescence].

A retrospective survey on the frequency of seizure-recurrence after drug withdrawal in all forms of adolescent seizures has been undertaken to detect possible prognostic criteria. Patients were selected according to 3 criteria: first seizure between 11 and 19 years of age; out-patients seen by one of us between 1955 and 1979 within the year of onset of epilepsy; all patients followed for at least 5 years after the first seizure. Two-hundred and seventy two patients entered the study.