Publications by authors named "M Pesonen"
Stress and psychological disorders are substantial public health concerns, necessitating innovative therapeutic strategies. This study investigated the psychophysiological benefits of nature-based soundscapes, drawing on the biophilia hypothesis. Using a randomized, acute cross-over design, 53 healthy participants experienced either a nature-based or a reference soundscape for 10 min, with a 2-min washout period.
View Article and Find Full Text PDFWhether the fat-soluble vitamins A, D, E, and K are associated with development of graft-versus-host disease (GvHD) after allogeneic stem cell transplantation, is unclear. We assessed if the levels of these vitamins were associated with development of GvHD during the first year after transplantation using data from a two-armed randomized nutritional intervention trial. Changes in plasma levels during 1-year follow-up were analyzed using a linear mixed model for repeated measurements.
View Article and Find Full Text PDFPurpose: The prevalence of chronic kidney disease (CKD) is increasing and CKD often goes undiagnosed and untreated until its later stages when irreversible damage has occurred. Patients with CKD have been reported to have lower quality of life than the general population, but the patient-reported outcome data on CKD patients in Finland are limited.
Patients And Methods: The primary outcome of this structural, multiple-choice survey study was to assess life satisfaction and experienced health status in Finnish patients with CKD.
Article Synopsis
- - We studied how exposure to different microbes at birth affects the behavior and temperament of children at ages 1, 2, and 3, using data from the Kuopio Birth Cohort Study and various behavioral questionnaires.
- - Microbial samples from babies’ mouths were analyzed to determine their diversity, with a focus on comparing those born with and without antibiotic exposure during delivery.
- - While no strong associations were confirmed after strict statistical corrections, initial findings suggested a possible link between microbial diversity and behaviors like surgency, especially for children exposed to antibiotics at birth.
Article Synopsis
- The study aimed to evaluate the risk and prevalence of hospital-acquired bacterial infections in intensive care units during the first wave of COVID-19 by using advanced deep-sequencing techniques.
- Conducted in a hard-hit region in northern Italy, the research involved collecting and analyzing samples from patients in both regular wards and ICUs to identify specific bacterial pathogens.
- The findings highlighted the effectiveness of this novel sequencing approach in tracking bacterial transmission and understanding antimicrobial resistance during a time of increased patient load.