Publications by authors named "M Perotto"
Aims: Accurate selection of patients with severe heart failure (HF) who might benefit from advanced therapies is crucial. The present study investigates the performance of the available risk scores aimed at predicting the risk of mortality in patients with severe HF.
Methods And Results: The risk of 1-year mortality was estimated in patients with severe HF enrolled in the HELP-HF cohort according to the MAGGIC, 3-CHF, ADHF/NT-proBNP, and GWTG-HF risk scores, the number of criteria of the 2018 HFA-ESC definition of advanced HF, I NEED HELP markers, domains fulfilled of the 2019 HFA-ESC definition of frailty, the frailty index, and the INTERMACS profile.
Purpose Of Review: Hot phases are a challenging clinical presentation in arrhythmogenic cardiomyopathy (ACM), marked by acute chest pain and elevated cardiac troponins in the absence of obstructive coronary disease. These episodes manifest as myocarditis and primarily affect young patients, contributing to a heightened risk of life-threatening arrhythmias and potential disease progression. This review aims to synthesize recent research on the pathophysiology, diagnostic challenges, and therapeutic management of hot phases in ACM.
View Article and Find Full Text PDFIn-hospital evolution of secondary mitral regurgitation in acutely decompensated heart failure.
J Cardiovasc Med (Hagerstown)
November 2024
Aims: Secondary mitral regurgitation (MR) negatively affects prognosis in acutely decompensated heart failure (ADHF), but can be rapidly sensitive to changes in volume status and medical interventions. We sought to assess the evolution of secondary MR in patients hospitalized for ADHF and its prognostic implications.
Methods: We retrospectively enrolled 782 patients admitted for ADHF with at least two in-hospital echocardiographic evaluations of MR.
Article Synopsis
- Secondary tricuspid regurgitation (TR) is linked to worse outcomes in patients with acute decompensated heart failure (ADHF), and this study investigates how TR changes during hospital treatment and its impact on patient prognosis.
- The research included 1054 ADHF patients, finding that nearly half (49%) of those with severe TR at admission improved during their hospital stay, which correlated with better recovery and lower long-term risk of dying or being readmitted for heart failure.
- Factors like atrial fibrillation and higher diuretic doses were associated with less likelihood of TR improvement, but better TR status was significantly tied to better 5-year survival rates and heart failure hospitalization outcomes.