High-performance wobbling subreflector for the Millimetre and Infrared Testa Grigia Observatory 2.6-m telescope.

The Millimetre and Infrared Testa Grigia Observatory 2.6-m Cassegrain telescope has been designed to allow high-sensitivity observations in the millimeter spectral range. For this purpose, in order to reduce unwanted contributions from local foregrounds, we adopted a sky-chopping technique, by wobbling the telescope subreflector.

In vivo inhibition of N-nitrosodimethylamine metabolism by 4-methylpyrazole: a model for endogenous nitrosation.

The endogenous formation of N-nitrosodimethylamine (NDMA) was investigated in the ferret by inhibiting metabolism and monitoring urinary NDMA levels. The addition of 1.0 mg/ml of 4-methylpyrazole (4-MP) to the drinking water was sufficient to allow a 13% urinary recovery of a 4.

Nitrite-cured meats as a source of endogenously and exogenously formed N-nitrosoproline in the ferret.

Nitrite-cured meat containing 120 mg Na15NO2/kg was fed to male ferrets (Mustela putorius furo). During consumption of the meat, the animals were dosed orally with 0.87 mmol [2-2H]proline.

The effects of fractionated thermally oxidized corn oil on drug-metabolizing enzyme systems in the rat.

Corn oil samples were heated, with aeration, to 210 degrees C for a total of 5 hr. Both fresh and oxidized samples were urea-fractionated and the individual fractions were administered to male Sprague-Dawley rats by gastric intubation. The effects of urea adducts, adduct-free fractions, non-saponifiable fractions and unfractioned fresh and thermally oxidized oil samples on hepatic, intestinal and colonic drug-metabolizing enzymes were determined.