Publications by authors named "M Pellicano"
Article Synopsis
- * Treatment focuses on reducing spleen size and alleviating symptoms, with patients evaluated as lower or higher risk for transplant eligibility; those not eligible usually receive long-term JAK inhibitor therapy.
- * Newer JAK inhibitors and combination treatments are under investigation to address the limitations of current therapies, such as limited efficacy and adverse effects, highlighting the need for ongoing research in this area.
Cancers (Basel)
September 2024
Article Synopsis
- This study examined the effects of D-VTd induction therapy on recovery after autologous stem cell transplantation in patients with newly diagnosed multiple myeloma (NDMM).
- Sixty patients received D-VTd while 80 others received VTd as a control, with results showing that D-VTd led to a slightly longer time for neutrophil and platelet recovery.
- Despite delayed engraftment in the D-VTd group and a higher incidence of febrile neutropenia, the study concluded that D-VTd does not negatively affect overall transplant safety outcomes.
Article Synopsis
- - Balloon aortic valvuloplasty (BAV) is a procedure used for patients with severe aortic valve stenosis, either as preparation for trans-catheter aortic valve replacement (TAVR) or alone in certain cases; the study focused on the newly available Mammoth balloon catheter (BC) used in this context.
- - A retrospective analysis was conducted on patients treated with the Mammoth BC at a hospital in Milan, where technical success was defined by the ability to successfully deploy and inflate the catheter without significant complications like injury or stroke.
- - The results showed a 100% technical success rate in 121 procedures with no complications attributed to the Mammoth BC; however, some patients in the stand-alone group
Can J Cardiol
November 2024
Article Synopsis
- Coronary access (CA) and percutaneous coronary intervention (PCI) can be more difficult after valve-in-valve transcatheter aortic valve replacement (ViV-TAVR), especially with certain valve designs.*
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- A study found that the ACURATE neo2 valve led to significantly better success rates for both CA (96.7%) and PCI (98.3%) compared to the Evolut PRO+ valve (75% and 85%, respectively).*
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- The design differences between the valves affected procedural approaches, with ACURATE neo2 allowing for easier access due to a greater valve-to-anatomy distance.*
