3D Printed Lenses for Vertical Beam Collimation of Optical Phased Arrays.

This article presents the design, fabrication, and characterization of edge-coupled 1D optical phased arrays (OPAs) combined with collimating lenses. Our concept was tested with two OPAs having different collimation ranges. Both OPA designs have 3-μm waveguide spacing and the maximum beam steering range is about 30° based on wavelength tuning around 1550 nm.

Additive manufacturing of double-sided centimeter-scale optics.

In this article we demonstrate rapid manufacturing of an illumination quality double-sided centimeter-scale optics without any post-processing. Two methods are presented: additive manufacturing (AM) using an optically transparent material with a water-soluble support material (support method), and alternatively, using only the optically transparent material but flipping the optics mid-process (flipping method). The main advantage of the flipping method is that only one material is needed.

Aberrant DNA methylation distorts developmental trajectories in atypical teratoid/rhabdoid tumors.

Atypical teratoid/rhabdoid tumors (AT/RTs) are pediatric brain tumors known for their aggressiveness and aberrant but still unresolved epigenetic regulation. To better understand their malignancy, we investigated how AT/RT-specific DNA hypermethylation was associated with gene expression and altered transcription factor binding and how it is linked to upstream regulation. Medulloblastomas, choroid plexus tumors, pluripotent stem cells, and fetal brain were used as references.

FURIN regulates cytotoxic T-lymphocyte effector function and memory cell transition in mice.

The proprotein convertase subtilisin/kexins (PCSKs) regulate biological actions by cleaving immature substrate proteins. The archetype PCSK, FURIN, promotes the pathogenicity of viruses by proteolytically processing viral proteins. FURIN has also important regulatory functions in both innate and adaptive immune responses but its role in the CD8 CTLs remains enigmatic.

Terahertz Absorber with Graphene Enhanced Polymer Hemispheres Array.

We propose an original technique for the fabrication of terahertz (THz) metasurfaces comprising a 3D printed regular array of polymer hemispheres covered with a thin conductive layer. We demonstrate that the deposition of a thin metal layer onto polymer hemispheres suppresses the THz reflectivity to almost zero, while the frequency range of such a suppression can be considerably broadened by enhancing the structure with graphene. Scaling up of the proposed technique makes it possible to tailor the electromagnetic responses of metasurfaces and allows for the fabrication of various components of THz photonics.