A canine model of reversible urethral sphincter insufficiency.

This study developed an animal model with internal and external urethral sphincter insufficiency by bypassing the sphincter without major damage so that the animal under study can return to normal life after the study. There is a need for a reliable, applicable, and reproducible animal model for studying urinary incontinency disease due to incorrect sphincter function. Seven adult male dogs were used for this study.

New insights into the taxonomy and the evolutionary relationships of the rare nematode genus Ferris & Ferris, 1973 (Nematoda, Dorylaimida, Belondiridae), after the molecular characterization of an Iranian population of its type species.

A new Iranian population of is characterized, including morphometrics, microphotographs, and molecular (18S, 28S rDNA) studies. It is compared with previously known populations. The results derived from molecular analyses failed to find close evolutionary relationships with other traditional genera of Belondiridae and Swangeriinae, adding more uncertainties about the internal phylogeny of the family.

Molecular Profiling of Mouse Models of Loss or Gain of Function of the KCNT1 (Slack) Potassium Channel and Antisense Oligonucleotide Treatment.

The potassium sodium-activated channel subtype T member 1 () gene encodes the Slack channel K1.1, which is expressed in neurons throughout the brain. Gain-of-function variants in are associated with a spectrum of epilepsy syndromes, and mice carrying those variants exhibit a robust phenotype similar to that observed in patients.

Injectable alginate chitosan hydrogel as a promising bioengineered therapy for acute spinal cord injury.

Dealing with spinal cord injuries presents problematic due to multiple secondary mechanisms. Beyond primary concerns like paralysis and disability, complications including urinary, gastrointestinal, cardiac, and respiratory disorders, along with substantial economic burdens may occur. Limited research focuses on modeling and treating contusion and compression injuries.

Morphological and Molecular Characterization of () Populations Parasitizing Pistachio in Kerman and Khorasan Razavi Provinces, Iran.

Root-knot nematodes (RKNs) are the most destructive nematode species in main pistachio cultivation areas of Iran, and adversely affect crop quality and yield. So far, and have been reported infecting pistachio. In this study, four populations of were found infecting pistachio in Kerman and Khorasan Razavi provinces.