Association of HLA-DRB1 and HLA-DQB1 with red-blood-cell alloimmunization in the Czech population.

Background And Objectives: Alloimmune antibodies against red-blood-cell (RBC) antigens induced in susceptible individuals (responders) by transfusion, pregnancy or transplantation may have serious clinical consequences. The aim of this study was to investigate association of alloimmunization against selected RBC antigens with HLA-Class II.

Materials And Methods: A total of 230 responders (106 monoresponders and 124 multiresponders) were enrolled into the study.

[Optimization of antibodies examanination against thrombocytes in pregnant and postpartum women].

Objective: To optimize thrombocyte antibodies examination in pregnant and postpartum women.

Design: Retrospective analysis.

Setting: Blood Center, Faculty Hospital and Medical Faculty Ostrava University, Ostrava.