Use of a propofol infusion for anaesthetic maintenance in Guinea pigs (Cavia porcellus): a retrospective case series.

Objective: To retrospectively evaluate the feasibility of a propofol infusion for anaesthetic maintenance in guinea pigs.

Study Design: Retrospective case series.

Animals: Client-owned guinea pigs undergoing general anaesthesia.

Development of a method for analysis of ketamine and norketamine enantiomers in equine brain and cerebrospinal fluid by capillary electrophoresis.

Ketamine and norketamine are being transported across the blood brain barrier and are also entering from blood into cerebrospinal fluid (CSF). Enantioselective distributions of these compounds in brain and CSF have never been determined. The enantioselective CE based assay previously developed for equine plasma was adapted to the analysis of these compounds in equine brain via use of an acidic pre-extraction of interferences prior to liquid/liquid extraction at alkaline pH.

Prevalence and risk factors for canine post-anesthetic aspiration pneumonia (1999-2009): a multicenter study.

Objective: To determine the incidence of canine post-anesthetic aspiration pneumonia (AP) and to identify anesthetic agents, procedures and management factors associated with the development of AP.

Study Design: Multicenter, randomized, case-controlled retrospective study.

Animals: Two hundred and forty dogs affected with AP and 488 unaffected control dogs.

Midazolam, as a co-induction agent, has propofol sparing effects but also decreases systolic blood pressure in healthy dogs.

Objective: To evaluate the effects of the co-administration of midazolam on the dose requirement for propofol anesthesia induction, heart rate (HR), systolic arterial pressure (SAP) and the incidence of excitement.

Study Design: Prospective, randomized, controlled and blinded clinical study, with owner consent.

Animals: Seventeen healthy, client owned dogs weighing 28 ± 18 kg and aged 4.

Intraoperative antinociception and postoperative analgesia following epidural anesthesia versus femoral and sciatic nerve blockade in dogs undergoing stifle joint surgery.

Objective: To compare analgesic efficacy of preoperative epidural anesthesia with efficacy of femoral and sciatic nerve blockade in dogs undergoing hind limb orthopedic surgery.

Design: Prospective randomized blinded clinical study.

Animals: 22 dogs requiring stifle joint surgery.