Publications by authors named "M Parnell"

Article Synopsis
  • - The study examines how the pH of the buffer and the choice of crosslinking ions (Calcium or Barium) affect the stability, printability, and cell viability of alginate-gelatin hydrogels used in bioengineering.
  • - Findings indicate that pH and crosslinking ions influence swelling, degradation rates, and cell metabolism, with U2OS cells showing increased activity at pH 8.0 and Ca ions, while Ba ions led to higher cell death in NIH/3T3 cells.
  • - Additionally, the arrangement of U2OS cells varies depending on the pH of the hydrogel, highlighting the significance of both buffer pH and crosslinking ions in determining hydrogel
View Article and Find Full Text PDF

Background/aims: To evaluate the efficacy and safety of the PreserFlo MicroShunt glaucoma device in a multicentre cohort study.

Methods: All consecutive patients who received the microshunt with mitomycin-C (MMC) 0.4 mg/mL from May 2019 to September 2020 in three UK tertiary centres.

View Article and Find Full Text PDF

Background: Cardiorespiratory fitness (CRF) and physical activity (PA) are associated with a plethora of positive health effects. Many UK children fail to meet the recommended level of PA, with an observed decline in CRF levels over recent decades. Second-hand tobacco smoke (SHS) is responsible for a significant proportion of the worldwide burden of disease, but little is understood regarding the impact of SHS exposure on CRF and PA in children.

View Article and Find Full Text PDF

Previous research has shown secondhand tobacco smoke to be detrimental to children's health. This qualitative study aimed to explore children from low socioeconomic status (SES) families and their reasons for being physically active, attitudes towards physical activity (PA), fitness and exercise, perceived barriers and facilitators to PA, self-perceptions of fitness and physical ability, and how these differ for children from smoking and non-smoking households. A total of 38 children (9-11 years; 50% female; 42% smoking households) from the deprived areas of North West England participated in focus groups ( = 8), which were analysed by utilizing thematic analysis.

View Article and Find Full Text PDF