Publications by authors named "M Palop-Cervera"
Objective: Patients with severe eosinophilic asthma experience high risk of exacerbations and reduced quality of life. Benralizumab, a monoclonal antibody binding to IL-5 receptor α subunit, is an approved drug for its treatment. The objective was to describe clinical remission after benralizumab prescription in routine clinical practice.
View Article and Find Full Text PDFBackground: The ORBE II study aimed to describe the characteristics and clinical outcomes of adult patients with severe eosinophilic asthma (SEA) treated with benralizumab in a real-world setting in Spain.
Methods: ORBE II (NCT04648839) was an observational, retrospective cohort study in adult SEA patients who had been prescribed benralizumab. Demographic and clinical data of 204 SEA patients were collected 12 months prior to benralizumab initiation (baseline) and at follow-up.
Background: COVID-19 disease is a serious global health problem. Few treatments have been shown to reduce mortality and accelerate time to recovery. The aim of this study was to evaluate the potential effect of a food supplement (probiotics, prebiotics, vitamin D, zinc and selenium) in patients admitted with COVID-19.
View Article and Find Full Text PDFAim: Severe asthma is a complex, heterogeneous condition that can be difficult to control despite currently available treatments. Multidisciplinary severe asthma units (SAU) improve control in these patients and are cost-effective in our setting; however, their implementation and development can represent an organizational challenge. The aim of this study was to validate a set of quality care indicators in severe asthma for SAU in Spain.
View Article and Find Full Text PDFArticle Synopsis
- Research aimed to compare COVID-19 impacts between older adults in long-term care facilities (LTCF) and those living in the community, focusing on clinical and epidemiological differences, hospital management, and outcomes.
- Among hospitalized patients aged 75 and older, LTCF residents were found to be older, more likely to have functional dependence, comorbidities, and dementia, and had shorter symptom durations than community-dwelling peers.
- Key mortality risk factors for LTCF residents included severe functional dependence and hypoxia; however, after adjusting for other factors, their in-hospital mortality rate was lower than initially observed.