Current Status of Magnetic Resonance Colonography for Screening and Diagnosis of Colorectal Cancer.

Magnetic resonance colonography with its high tissue contrast and without the use of ionizing radiation was designed as a minimally invasive screening tool for colorectal cancer and its precursors. Nonetheless, heterogeneous data on diagnostic performance and patient burden have hindered its use in screening. This article provides an overview on the status and potential of magnetic resonance colonography in the setting of detection and screening of colorectal cancer and its precursors.

Magnetic resonance colonography with a limited bowel preparation and automated carbon dioxide insufflation in comparison to conventional colonoscopy: patient burden and preferences.

Objectives: To evaluate patient burden and preferences for MR colonography with a limited bowel preparation and automated carbon dioxide insufflation in comparison to conventional colonoscopy.

Methods: Symptomatic patients were consecutively recruited to undergo MR colonography with automated carbon dioxide insufflation and a limited bowel preparation followed within four weeks by colonoscopy with a standard bowel cleansing preparation. Four questionnaires regarding burden (on a five-point scale) and preferences (on a seven-point scale) were addressed after MR colonography and colonoscopy and five weeks after colonoscopy.

Magnetic resonance colonography with automated carbon dioxide insufflation: Diagnostic accuracy and distension.

Objectives: To evaluate the diagnostic performance of MR colonography using automated carbon dioxide (CO2) insufflation for colonic distension, with colonoscopy serving as the reference standard.

Methods: Ninety-eight symptomatic patients underwent MR colonography with faecal tagging and automated CO2 insufflation. Three readers (one expert (reader 1), and two less experienced (readers 2 and 3)) evaluated the images for the presence of colorectal lesions.

Magnetic resonance colonography for screening and diagnosis of colorectal cancer.

Colorectal cancer is the second most common cause of cancer-related death in Europe and the United States, and a major cause of mortality. Early detection of colorectal cancer and its precursors reduces mortality and morbidity, and a minimally invasive screening tool is essential for high patient acceptance and participation. To achieve this goal, computed tomographic colonography and magnetic resonance (MR) colonography have been introduced.