An international observational study assessing conservative management in hemorrhoidal disease: results of CHORALIS (aCute HemORrhoidal disease evALuation International Study).

Real-world evidence on the management of hemorrhoidal disease (HD) is limited. This international study collected clinical practice data on the effectiveness of conservative treatments for acute HD on symptoms and quality of life (QoL), providing perspectives of treatment modalities from different continents. The 4-week observational prospective CHORALIS study involved adult outpatients consulting for spontaneous complaints of hemorrhoids (graded using Goligher classification) and prescribed conservative treatments according to usual clinical practice.

INFLUENCE OF A VARIETY OF SUTURE MATERIAL ON THE ANAL CANAL WOUNDS HEALING AFTER COMBINED OPERATIONS CONCERNING THE COMBINED ANORECTAL PATHOLOGY WITH USING OF MODERN TECHNOLOGIES.

The urgency of the problem of combined pathology of the anal canal and rectum is quite high due to the lack of a unified approach to surgical treatment of this category of patients. The aim of the study was to conduct a comparative morphological assessment of postoperative wound healing in patients with combined anorectal pathology after combined operations using different types of suture material, as well as modern high-frequency electrosurgery and radio-wave surgery devices. The dynamics of the wound process under the influence of caprosin (3/0) and polysorb (3/0) was performed on 60 patients from the first and second study groups, where radio-frequency device "Surgitron" and high-frequency electrosurgery device "KLS Martin" were used for surgical treatment, as they had approximately the same depth of coagulation tissue necrosis, by cytological examination of smears-imprints from the surface of postoperative wounds on 3, 5, 7, 14 and 21 days.

THE RESULTS OF SURGICAL TRATMENT OF COMBINED ANORECTAL DISEASES USING RADIO-FREQUENCY AND HIGH-FREQUENCY ELECTROSURGICAL DEVICES.

The combined pathology of the anal canal and rectum is a very important problem today, due to its progressive growth, especially in industrialized countries over the past two or three decades. The aim of the study was to conduct a comparative assessment of using high-frequency electrosurgical devices and also radio-frequency device for treatment of combined anal саnal and rectal pathology. The results of treatment of 635 patients with combined anal canal and rectal diseases have been analyzed.

[EXPERIENCE OF APPLICATION OF THE ELECTRIC WELDING METHOD FOR BIOLOGICAL TISSUES IN URGENT AND ELECTIVE SURGERY].

The usage experience of the electric welding technologies for biological tissues in 158 patients, while applying Ukrainian high—frequency generator ЕК 300 М1, was presented. Laparoscopic appendectomy, laparoscopic plasty of inguinal hernia, laparoscopic cholecystectomy, open resection of small and large bowel, during which the method of electric welding of biological tissues was applied, had constituted the main surgical interventions. The electric welding usage have permitted to reduce the operation time and the blood volume loss, and also the clipses quantity needed, which are applied for the hemostasis completion and hermetization of anatomic structures after their transsection.

[DETERMINATION OF A FATTY ACIDS CONTENT IN BILIARY LIPIDS AS A PROGNOSTIC FACTOR FOR THE COMPLICATIONS OCCURRENCE IN PATIENTS AFTER OPERATIONS FOR AN ACUTE CHOLECYSTITIS IN A HIGH OPERATIVE—ANESTHESIOLOGICAL RISK].

Investigation was conducted with objective to establish a prognostic significance of the fatty acids content in biliary lipids for the complications occurrence in patients, operated on for an acute cholecystitis, while presence of high operative—anesthesiological risk. A fatty acids content in biliary lipids was analyzed in 64 patients in presence of moderate (grade ІІ) and severe (grade ІІІ) course of the disease. Coefficients К1 and К2 for prognostication of postoperative purulent—inflammatory complications occurrence were elaborated, their threshold level (К1=0.