Publications by authors named "M P Semmler"
Article Synopsis
- The study investigates how airflow and fiber tension affect voice production by analyzing the oscillation of vocal folds using a synthetic larynx model.
- It involved 76 experiments measuring various factors like vocal fold motion and sound output, with a focus on how flow rate and tension vary.
- Results showed that while flow rate mainly influences phonation characteristics, the fundamental frequency and quality of the sound are largely determined by the tension of the vocal folds.
The primary acoustic signal of the voice is generated by the complex oscillation of the vocal folds (VFs), whereby physicians can barely examine the medial VF surface due to its anatomical inaccessibility. In this study, we investigated possibilities to infer medial surface dynamics by analyzing correlations in the oscillatory behavior of the superior and medial VF surfaces of four human hemilarynges, each in 24 different combinations of flow rate, VF adduction, and elongation. The two surfaces were recorded synchronously during sustained phonation using two high-speed camera setups and were subsequently 3D-reconstructed.
View Article and Find Full Text PDF3D reconstruction of vocal fold dynamics with laser high-speed videoendoscopy in children.
Laryngoscope Investig Otolaryngol
October 2024
Objective: The objective of this study is to evaluate three-dimensional vertical motion of the superior surface of the vocal folds in vivo in (a) typically developing children as a function of vocal frequency variations and (b) a child with vocal nodules.
Methods: A custom developed laser endoscope coupled with high-speed videoendoscopy was used to obtain 3D parameters from 2 healthy children, one child with vocal nodules, and 23 vocally healthy adults (females = 11, males = 12). Parameters of amplitude (mm), maximum opening/closing velocity (mm/s), and mean opening/closing velocity (mm/s) were computed for the lateral and vertical vibratory motion along the anterior, middle, and posterior sections of the vocal folds were computed.
Objective: This study investigates relationships between the oscillation behavior of the medial and superior vocal fold (VF) surfaces during sustained phonation in a human cadaver hemilarynx.
Methods: An experimental test stand synchronously captured the medial and superior VF surfaces of a human ex vivo hemilarynx during sustained phonation using two high-speed camera setups in 24 experimental settings. The 3D coordinates of the medial VF surface were reconstructed by triangulation of sewn-in marker points, while laser-based reconstruction was used for the superior VF surface.
Article Synopsis
- Photodynamic diagnosis (PDD) improves bladder cancer detection during transurethral resection of bladder tumor (TURBT), but its everyday implementation is not fully assessed.
- An analysis of Germany's patient data from 2010 to 2021 revealed that PDD use increased two-fold, with PDD patients being younger and discharged earlier yet incurring about €500 more in costs.
- PDD was associated with lower rates of transfusions, ICU admissions, and 30-day mortality compared to traditional white-light TURBT, though it also had slightly higher rates of bladder perforation and reoperations, indicating more research is needed before it becomes standard practice.