Plinia cauliflora (Mart.) Kausel (Jaboticaba) leaf extract: In vitro anti-Trypanosoma cruzi activity, toxicity assessment and phenolic-targeted UPLC-MS metabolomic analysis.

Ethnopharmacological Relevance: Plinia cauliflora (Mart.) Kausel, known as Brazilian grape or jaboticaba, is widely used in Brazilian traditional medicine to treat infectious and inflammatory disorders. However, several aspects of its biological potential remain unclear, such as toxicity and effects on pathogenic protozoa.

Profile of phenolic compounds in jabuticaba ( sp.) a potential functional ingredient.

Phenolic compounds have attracted a lot of attention due to their benefits to human health. Jabuticaba () fruit has been described as an excellent source of these compounds, while Jabuticaba leaf, considered as plant residue, has shown functional effects. The present study aimed to characterize the phenolic profile in two different leaves extracts (hydroalcoholic ethanol and butanol) of by UPLC-ESI-QTOF-MS.

Pneumonia hospitalization in Brazil from 2003 to 2007.

Objectives: In emerging countries, pneumonia is a leading cause of hospitalization and death, particularly among the youngest and oldest. This retrospective study aimed to quantify the incidence of hospitalization due to all-cause pneumonia (HDTP) and in-hospital case fatality rates (CFRs) in all age groups, in five administrative regions of Brazil.

Methods: The International Classification of Diseases Tenth Revision coding for pneumonia (J12-J18) and an interactive web-based database of individuals covered by the Unified Health System in Brazil who were hospitalized from 2003 to 2007, were used to identify cases.

Frequency of complications of mitral valve prolapse in subjects aged 60 years and older.

One hundred forty-five patients (74 women, 71 men), aged 60 years and older, with echocardiographically documented mitral valve prolapse were studied. One hundred sixteen patients had precordial systolic murmurs, 20 of whom were suspected of having mitral valve prolapse before the echocardiographic study. Infective endocarditis occurred in 7 patients, cerebral ischemic events in 13 and spontaneous rupture of chordae tendineae in 33.