Colorimetric Detection of Bovine Serum Albumin (BSA Protein) by Interaction and Modification of Silver Nanoparticles.

The detection of serum albumin is of great relevance because its presence in urine above normal levels is implicated in different pathologies, such as Diabetes Mellitus and Preeclampsia. The main objective of this work was to develop a protocol to sense serum albumin using the well-known unusual optical phenomenon that nanoparticles present, which is called surface plasmon resonance (SPR), as well as the influence of proteins on the size and morphology of nanoparticles, and consequently, on the SPR. The interaction of these nanoparticles with proteins forms biocoronates, which modify the optical and morphological properties of nanostructures.

Derived Neutrophil-to-Lymphocyte and Neutrophil-to-Platelet Ratios Distinguish Sinusitis-Related Orbital Cellulitis From Periorbital Necrotizing Fasciitis.

Purpose: Periorbital necrotizing fasciitis (NF) and sinusitis-related orbital cellulitis (OC) present with common clinical features, although the management algorithms for these ailments vary considerably. Previous investigations have failed to identify biomarkers that distinguish between these entities. This study was designed to explore the role of the derived neutrophil-to-lymphocyte and neutrophil-to-platelet ratios in discerning NF from OC.

Genital infections in high-risk human papillomavirus positive Paraguayan women aged 30-64 with and without cervical lesions.

Objective: To determine the prevalence of genital infections (GIs), including sexual transmitted STIs: Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, Trichomonas vaginalis, and opportunistic pathogens that generally do not cause STIs, non-classic STI: Ureaplasma urealyticum, Ureaplasma parvum and Mycoplasma hominis, in women with high-risk oncogenic human papillomavirus (hr-HPV) infection and their association with cervical lesions.

Methods: A cross-sectional study was carried out including 231 hr-HPV positive women. Of these, 46 has histologically confirmed cervical intraepithelial neoplasia 3 (CIN3) or more (including CIN3 and cervical cancer lesions-CIN3+).

Factor model for ordinal categorical data with latent factors explained by auxiliary variables applied to the major depression inventory.

In behavioral and social research, questionnaires are an important assessment tool, through which individuals can be categorized according to how they classify themselves in respect to a personal trait. One example is the Major Depression Inventory (MDI), which is widely used for the assessment of depression. It can also be used as a depression severity scale, with scores ranging from 0 to 50 constructed considering the same weight for each item in the MDI.