Publications by authors named "M P PRIES"

Article Synopsis
  • Biallelic loss-of-function variants in the TBC1D2B gene have been linked to cognitive impairment and seizures in individuals, often accompanied by gingival overgrowth.
  • This study reports on five new cases of TBC1D2B variants, including analysis of molecular and clinical features in a total of ten subjects, revealing different types of mutations and their impact on the TBC1D2B protein levels.
  • The TBC1D2B disorder is characterized by progressive neurological decline, gingival overgrowth, and abnormal jaw morphology, potentially linked to defects in autophagy and the endolysosomal system affecting neuronal health.
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In the present study, a drinking amount of 10 L of milk replacer (MR) was allowed to dairy calves in order to approach the natural drinking behavior. The question is: how much protein is required by calves in order to achieve an intended growth rate? For this reason, sixty-eight pre-weaned Holstein calves were divided into two groups and fed with 10 L/d of MR containing either 22% protein (MR22) or 19% protein (MR19) at an almost comparable energy intake. Effects on performance, metabolic status, and health were compared.

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Extensive experimentation on individual animals in respiration chambers has already been carried out to evaluate the potential of dietary changes and opportunities to mitigate CH₄ emissions from ruminants. Although it is difficult to determine the air exchange rate of open barn spaces, measurements at the herd level should provide similarly reliable and robust results. The primary objective of this study was (1) to define a validity range (data classification criteria (DCC)) for the variables of wind velocity and wind direction during long-term measurements at barn level; and (2) to apply this validity range to a feeding trial in a naturally cross-flow ventilated dairy barn.

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Article Synopsis
  • The study evaluated the impact of condensed tannins (CT) from Black Wattle bark on dairy cows' milk production and nitrogen (N) efficiency.
  • During a 169-day trial with 96 lactating Holstein cows, two groups (control and experimental) were fed different rations, with the experimental group receiving varying percentages of CT supplementation.
  • Results showed that while CT3 reduced milk protein yield and nitrogen efficiency, it did not improve overall milk yield, suggesting that this supplement may not be beneficial for high-yielding dairy cows.
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Parturition is one of the most important events in reproduction. Regardless of many studies, exact time for pregnancy termination and onset of parturition is impossible to determine. The aim of this study was to describe and to compare protein profile of plasma from healthy pregnant cows (n = 6) at following five time points: 2 weeks, 1 week before, at parturition, 1 week and 2 weeks after parturition to search for possible protein markers of parturition.

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