Publications by authors named "M P Nicolino"
The natural history of type 1 diabetes (T1D) evolves from stage 1 (islet autoimmunity with normoglycemia; ICD-10 diagnostic code E10.A1) to stage 2 (autoimmunity with dysglycemia; E10.A2) and subsequent clinical stage 3 (overt hyperglycemia), which is commonly the first time of referral.
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- Achondroplasia is a genetic condition that leads to significant short stature and various medical challenges, and infigratinib is a new treatment being tested for children affected by this disorder.
- A phase 2 study involved 72 children aged 3 to 11, testing varying doses of infigratinib over 6 months, with adjustments possible during a further 12-month period, focusing on the safety and height growth of the participants.
- Results indicated that all participants experienced mild to moderate side effects, but none stopped treatment; most significantly, children in the highest dose group showed a notable increase in height growth compared to baseline, suggesting the treatment could be effective.
Article Synopsis
- The transition from pediatric to adult diabetes care for individuals with type 1 diabetes (T1D) is a challenging phase that needs more understanding, focusing on the experiences and satisfaction of young adults in France.
- An online survey was conducted with 104 participants to gather insights about their transition experience, revealing that many faced significant diabetes management issues post-transition.
- Key factors for a successful transition included early interactions with adult care teams, allowing participants to choose their transition age, and maintaining good diabetes control before leaving pediatric care.
Fatal giant craniofacial fibrous dysplasia in a very young child.
J Stomatol Oral Maxillofac Surg
July 2024