The MICA and MICB molecules, expressed on the cell membrane in response to cellular stress or cancer transformation, pose significant challenges for immunoassays. They exhibit high sequence and structural similarity, alongside considerable allelic polymorphism, with 291 and 53 known protein sequences, respectively. Some researchers treat MICA and MICB as a unified target because of their structural and functional similarities, while others distinguish between them.
View Article and Find Full Text PDFProbl Radiac Med Radiobiol
December 2024
Objective: to study the level of psychosocial strain in the able-bodied population of the NPP surveillance zone (SZ) and factors that shape it under the wartime posture and possible terrorist acts.
Methods: sociological (population survey), psychosocial (psychodiagnostic testing), analytical, mathematical i.e.
Mental imagery is a crucial cognitive process, yet its underlying neural mechanisms remain less understood compared to perception. Furthermore, within the realm of mental imagery, the somatosensory domain is particularly underexplored compared to other sensory modalities. This study aims to investigate the influence of tactile imagery (TI) on cortical somatosensory processing.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
December 2024
Spinal muscular atrophy (SMA) is a group of genetically heterogeneous neuromuscular diseases characterized by the progressive loss of motor neurons in the anterior horns of the spinal cord. The prevalence of SMA is approximately 1 in 10.000 live births.
View Article and Find Full Text PDFThis perspective considers the novel concept of olfactory neurofeedback (O-NFB) within the framework of brain-computer interfaces (BCIs), where olfactory stimuli are integrated in various BCI control loops. In particular, electroencephalography (EEG)-based O-NFB systems are capable of incorporating different components of complex olfactory processing - from simple discrimination tasks to using olfactory stimuli for rehabilitation of neurological disorders. In our own work, EEG theta and alpha rhythms were probed as control variables for O-NFB.
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