Publications by authors named "M P Moriarty"
Purpose: To determine if difference in Hounsfield Units (HU) of the medullary bone between the injured and non-injured femurs in patients with greater trochanteric fractures is associated with occult intertrochanteric (IT) extension.
Methods: Retrospective review was performed of 81 patients (age range 54-102, 54 females and 27 males) who underwent CT and subsequent MRI after identification of a greater trochanteric fracture without evidence of IT extension on radiography and/or CT. Hounsfield units of the injured and non-injured femurs on CT were recorded at the level of the base of the greater trochanter centrally (ROI1) and the level of the upper border of the lesser trochanter posteromedially (ROI2).
Rabbit hemorrhagic disease virus 2 (RHDV2; , ), the cause of a highly transmissible and fatal lagomorph disease, has spread rapidly through the western United States and Mexico, resulting in substantial mortality in domestic and wild rabbits. The disease was first detected in California in May 2020, prompting an interagency/zoo/academia/nonprofit team to implement emergency conservation actions to protect endangered riparian brush rabbits () from RHDV2. Prior to vaccinating wild rabbits, we conducted a vaccine safety trial by giving a single SC dose of Filavac VHD K C+V (Filavie) vaccine to 19 adult wild riparian brush rabbits captured and temporarily held in captivity.
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- A unique enzootic focus of Mycobacterium bovis in free-ranging deer was identified in Michigan, leading to human cases linked to these deer between 1994 and 2022; four new cases were confirmed using genomic epidemiology.
- Genetic analysis showed a close connection between human and animal strains, with some cases having minimal genetic differences from deer and cattle isolates.
- Ongoing transmission of M. bovis from deer to humans and cattle poses a public health risk, prompting the need for future studies and a One Health approach to tackle TB transmission effectively.
Many pathogens of humans and livestock also infect wildlife that can act as a reservoir and challenge disease control or elimination. Efficient and effective prioritization of research and management actions requires an understanding of the potential for new tools to improve elimination probability with feasible deployment strategies that can be implemented at scale. Wildlife vaccination is gaining interest as a tool for managing several wildlife diseases.
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- A study analyzed the impact of the highly pathogenic avian influenza A(H5N1) virus on 67 wild mammals in the U.S. from April to July 2022.
- The affected species included primarily red foxes, but also striped skunks, raccoons, bobcats, Virginia opossums, coyote, fisher, and gray fox.
- Infected mammals exhibited neurological issues and had significant lesions like meningoencephalitis and pneumonia, suggesting that the virus spilled over from wild birds to these terrestrial animals.