Publications by authors named "M P Malter"
Article Synopsis
- - Autoantibodies against Caspr2 are linked to limbic autoimmune encephalitis and pain, with 36% of patients in a study experiencing pain, which is often severe and sometimes the main symptom.
- - Two main pain phenotypes were identified: distal-symmetric burning pain and widespread pain with myalgia/cramps, highlighting variability among patients.
- - There is a correlation between anti-Caspr2 autoantibodies and pre-existing chronic pain risk factors, suggesting that these autoantibodies could indicate decreased pain sensitivity, warranting testing in patients with different types of pain.
Purpose: Seizures occurring at the immediate onset of a stroke, abbreviated "seizures at onset" (SaO), pose a diagnostic and therapeutic challenge for physicians. In this study, we report on the current clinical practice in managing stroke patients with SaO from a large tertiary stroke center in Germany.
Methods: We selected all patients with SaO and acute ischemic or hemorrhagic stroke admitted to the Department of Neurology at the University Hospital of Cologne between 2019 and 01-01 and 2020-12-31.
Background: Acute symptomatic epileptic seizures are frequently seen in neurocritical care. To prevent subsequent unprovoked seizures, long-term treatments with antiseizure medications are often initiated although supporting evidence is lacking. This study aimed at prospectively assessing the risk of unprovoked seizure relapse with respect to the use of antiseizure medications.
View Article and Find Full Text PDFBackground And Purpose: Status epilepticus (SE) is a neurological emergency due to prolonged seizure activity or multiple seizures without full recovery in between them. Prehospital SE management is crucial since its duration is correlated with higher morbidity and mortality rates. We examined the impact of different therapeutic strategies in the prehospital setting with a focus on levetiracetam.
View Article and Find Full Text PDFObjective: Super-refractory status epilepticus (SRSE) is an enduring or recurring SE after 24 h or more of general anesthesia. This study aimed to evaluate the efficacy and safety of phenobarbital (PB) for the treatment of SRSE.
Methods: This retrospective, multicenter study included neurointensive care unit (NICU) patients with SRSE treated with PB between September 2015 and September 2020 from six participating centers of the Initiative of German NeuroIntensive Trial Engagement (IGNITE) to evaluate the efficacy and safety of PB treatment for SRSE.