Publications by authors named "M P Kiczek"

Article Synopsis
  • Rheumatic diseases can lead to various central nervous system (CNS) issues, including strokes, seizures, and headaches, along with demyelinating conditions like optic neuritis.* -
  • CNS problems often occur alongside other systemic symptoms of the rheumatic disease, but in some cases, neurological symptoms may be the first indication of the disease.* -
  • The review focuses on different rheumatic diseases that affect the CNS and highlights neuroimaging findings in affected patients.*
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Background And Objectives: Without brain biopsy, there are limited diagnostic predictors to differentiate primary angiitis of the CNS (PACNS) from intracranial atherosclerotic disease (ICAD). We examined the utility of clinical, CSF, and quantitative vessel wall magnetic resonance imaging (VWMRI) variables in predicting PACNS from ICAD.

Methods: In this cross-sectional design, observational study, we reviewed electronic medical records to identify patients (18 years and older) who presented to our medical center between January 2015 and December 2021 for ischemic stroke due to intracranial vasculopathy.

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Primary CNS vasculitis (CNSV) is a rare, idiopathic autoimmune disease that, if untreated, can cause significant morbidity and mortality. It is a challenging diagnosis due to multiple mimics that can be difficult to differentiate, given that the CNS is an immunologically privileged and structurally isolated space. As such, diagnosis requires comprehensive multimodal investigations.

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