Object-based feedback attention in convolutional neural networks improves tumour detection in digital pathology.

Human visual attention allows prior knowledge or expectations to influence visual processing, allocating limited computational resources to only that part of the image that are likely to behaviourally important. Here, we present an image recognition system based on biological vision that guides attention to more informative locations within a larger parent image, using a sequence of saccade-like motions. We demonstrate that at the end of the saccade sequence the system has an improved classification ability compared to the convolutional neural network (CNN) that represents the feedforward part of the model.

Fairness in AI for healthcare.

Artificial intelligence (AI) is a technology that enables computers to simulate human intelligence and has the potential to improve healthcare in a multitude of ways. However, there are also possibilities that it may continue, or exacerbate, current disparities. We discuss the problem of bias in healthcare and AI, and go on to highlight some of the ongoing and future solutions that are being researched in the area.

Variants in the L12 linker domain of KRT10 are causal to atypical epidermolytic ichthyosis.

Epidermolytic ichthyosis (EI) is a type of congenital ichthyosis, characterized by erythema and blistering at birth followed by hyperkeratosis. EI is caused by pathogenic variants in the genes KRT1 and KRT10, encoding the proteins keratin 1 (KRT1) and keratin 10 (KRT10), respectively, and is primarily transmitted by autosomal-dominant inheritance, although recessive inheritance caused by nonsense variants in KRT10 is also described. The keratins form a network of intermediate filaments and are a structural component of the cytoskeleton, giving strength and resilience to the skin.

Equine cheek tooth repulsion using small diameter repulsion pins: 20 cases.

Background: Reported complication rates after dental repulsion for equine exodontia are high (up to 80%), but repulsion methods have changed notably in the last 20 years.

Objectives: Describe the outcome for 20 cases after dental repulsion using small diameter repulsion pins.

Study Design: Retrospective case series.