Human mesenchymal stem cells (hMSCs) present an attractive target for cell therapy given their wide availability, immunomodulatory properties, and multipotent nature for differentiation into chondrocytes, osteocytes, and adipocytes. With the progression of hMSC clinical studies, there is an increasing demand for development of technologies that enable efficient cell scale-up into clinically relevant quantities. Commercial scale manufacturing of hMSCs will require a large surface area which is not cost effective with available two-dimensional culture vessels.
View Article and Find Full Text PDFPurpose: We present the validation data of the French version of a new quality of life questionnaire, specifically developed for use with older adults (>60 years old): the WHOQOL-OLD module. This questionnaire, which contains 24 items in six domains, is a complementary module of the WHOQOL-BREF quality of life questionnaire. It was internationally developed by a World Health Organization (WHO) group.
View Article and Find Full Text PDFThe French national agency for the assessment and quality of social and medical-social institutes and services (ANESM) recently published recommendations aiming to promote the quality of life of elderly people in nursing homes. These recommendations take into account the specific characteristics of the quality of life of this sector of the population.
View Article and Find Full Text PDF