Publications by authors named "M P Gogoi"
Article Synopsis
- α-Fluoro-α'-aryl ketones are important compounds in the fields of pharmaceuticals and agrochemicals, but their synthesis can be challenging, especially for unsymmetrical versions.
- This study introduces a one-pot method for synthesizing these compounds using a combination of ynamide, aryl boronic acid, and a fluorine source under palladium (Pd) catalysis.
- The researchers conducted control experiments and DFT studies to propose a reaction mechanism that includes the formation of acetic acid during the process.
Article Synopsis
- - This study investigates the health benefits of ripe Meyna spinosa fruit extracts, focusing on their abilities to act as antioxidants, antiproliferatives, and anti-inflammatories, supported by chemical analysis identifying key bioactive compounds.
- - The ethyl acetate extract showed the highest antioxidant activity, while both ethyl acetate and methanol extracts reduced cancer cell growth significantly and demonstrated strong anti-inflammatory effects by decreasing levels of various inflammatory markers in immune cells.
- - In animal models, the ethyl acetate extract effectively reduced swelling from carrageenan-induced inflammation by 23.45%, suggesting potential therapeutic applications for inflammation and cancer treatment.
Introduction: Understanding how RNA viral load changes (viral load kinetics) during acute infection in SARS-CoV-2 can help to identify when and which patients are most infectious. We seek to summarise existing data on the longitudinal RNA viral load kinetics of SARS-CoV-2 sampled from different parts of the respiratory tract (nose, nasopharynx, oropharynx, saliva and exhaled breath) and how this may vary with age, sex, ethnicity, immune status, disease severity, vaccination, treatment and virus variant.
Methods And Analysis: We will conduct a systematic review and meta-analysis, using studies identified through MEDLINE and EMBASE (via Ovid).
In the past decade, significant advances have been made in the field of chiral separation, which is crucial for biological and pharmaceutical applications. Enantioselective membranes have emerged as a promising platform for efficient chiral separation due to their unique properties such as large surface area, tunable pore size, and high selectivity. These membranes are particularly effective in separating enantiomers because of their ability to facilitate selective interactions between the membrane material and chiral molecules.
View Article and Find Full Text PDFObjectives: To assess how ethnicity, migration status and occupation are associated with healthcare workers (HCW) redeployment experiences during COVID-19 in a nationwide ethnically diverse sample.
Design: A cross-sectional analysis using data from the nationwide United Kingdom Research Study into Ethnicity And COVID-19 outcomes in Healthcare workers (UK-REACH) cohort study.
Setting: Healthcare settings.