Publications by authors named "M P Gatto"

This study investigates the degradation behavior of three distinct Fe-based alloys immersed in three pseudo-physiological solutions. These alloys, which have varied Mn and C contents, include a commercially available Fe-0.15C alloy, namely Fe-C, and two newly developed alloys, that is Fe-5Mn-0.

View Article and Find Full Text PDF
Article Synopsis
  • HE4 is a protein that helps promote fibrosis by preventing collagen breakdown; this study aimed to evaluate HE4 as a biomarker for interstitial lung disease (ILD) in patients with idiopathic inflammatory myopathies (IIMs).
  • Researchers enrolled 90 IIMs patients and 42 healthy controls, finding that serum HE4 levels were significantly higher in patients with IIMs, particularly in those diagnosed with ILD.
  • The study concluded that HE4 levels could serve as a useful biomarker for detecting and assessing ILD in IIMs patients, although there was no significant link between baseline HE4 and progressive fibrosing ILD in follow-up cases.
View Article and Find Full Text PDF

Infectious catheter-related right atrial thrombus (CRAT) is a potentially fatal but often underestimated contingency associated with central venous catheter (CVC) in patients on hemodialysis. Management guidelines for CRAT are lacking, and its occurrence poses clinical challenges. Here, we describe the case of an infectious CRAT in a young patient on hemodialysis with peculiar clinical complications and perform a literature review.

View Article and Find Full Text PDF

Lineage-specific transcription factors operate as master orchestrators of developmental processes by activating select cis-regulatory enhancers and proximal promoters. Direct DNA binding of transcription factors ultimately drives context-specific recruitment of the basal transcriptional machinery that comprises RNA polymerase II (RNAPII) and a host of polymerase-associated multiprotein complexes, including the metazoan-specific Integrator complex. Integrator is primarily known to modulate RNAPII processivity and to surveil RNA integrity across coding genes.

View Article and Find Full Text PDF