[Effects of non-clostridial anaerobic infection on the course of chronic pulmonary tuberculosis in experimental animals].

Influence of non-clostridial anaerobic infection on the course of chronic pulmonary tuberculosis caused by intrapleural administration of BCG used in a vaseline-lanolin mixture was studied experimentally on guinea pigs. Administration of Bacteroides fragilis in the presence of a mild tuberculous inflammation aggravates the course of a specific process promoting pleural empyema development, increase in the size of pulmonary granuloma, extension of pathologic changes into the parenchymatous organs and aggravation of a nonspecific inflammatory reaction. Animals with mixed infection exhibited a longer duration and higher level of M.

[The etiologic significance of ultrafine forms of the causative agent of tuberculosis in the development of sarcoidosis of the respiratory organs].

Pathological material, i. e. bronchoalveolar lavage fluid (BALF) and blood plasma from patients with various pathological processes in the lungs was studied.

[Dynamics of the shedding of bacterial and ultrafine forms of mycobacteria during the chemotherapy of patients with pulmonary tuberculosis].

The specific features of bacterial excretion by patients with pulmonary tuberculosis in the process of chemotherapy, depending on the duration of treatment, have been studied, and the time-course of the excretion of ultramicro forms of mycobacteria by patients with and without caverns in the lungs in the process of chemotherapy has been followed. The results of the detection of M. tuberculosis ultramicro forms with the use of the biological and bacteriological methods indicate that both these methods are highly effective and informative.