Publications by authors named "M P Domingo"

Previous works show the key role of electrostatics in the SARS-CoV-2 virus in aspects such as virus-cell interactions or virus inactivation by ionic surfactants. Electrostatic interactions depend strongly on the variant since the charge of the Spike protein (responsible for virus-environment interactions) evolved across the variants from the highly negative Wild Type (WT) to the highly positive Omicron variant. The distribution of the charge also evolved from diffuse to highly localized.

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Anthropogenic pressures and climate change present growing challenges for cetaceans, as the combined effects of multiple stressors can jeopardize their welfare and survival. In this context, validating reliable individual welfare indicators is crucial for quantifying these impacts. This study aimed to validate a method for measuring cortisol and oxytocin from the epidermis of stranded striped dolphins (Stenella caeruleoalba) using enzyme immunoassays, while accounting for confounding factors such as epidermal layer and body location.

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Article Synopsis
  • The study investigates the prevalence and impact of inter-atrial block (IAB) as an indicator of electrical dysfunction in patients with heart failure with preserved ejection fraction (HFpEF).
  • It examines two groups: ambulatory HFpEF patients and those recently hospitalized, assessing their risk for adverse events like hospitalization and death.
  • Findings suggest that different stages of electrical atrial dysfunction significantly predict adverse outcomes, indicating that patients without dysfunction might require less intensive management.
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Article Synopsis
  • - Porcine dermatitis and nephropathy syndrome (PDNS) is a serious condition affecting pigs, mainly linked to porcine circovirus 2 (PCV-2) and potentially associated with other strains (PCV-3 and PCV-4).
  • - A study analyzed 102 PDNS cases through various methods like PCR and immunohistochemistry to investigate the presence of different porcine circoviruses.
  • - Results showed that all PDNS cases tested positive for PCV-2, with a subset also showing PCV-3, while no link was found between PDNS and PCV-1 or PCV-4, reinforcing the idea that PCV-2 is likely the primary cause of PDNS
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