Publications by authors named "M P De Santo"

Introduction: This study aimed to evaluate the short-term and long-term skeletal and dental asymmetry with miniscrew-assisted rapid palatal expansion (MARPE), rapid palatal expansion (RPE), and control group using cone-beam computed tomography (CBCT) analysis.

Methods: A total of 180 CBCT scans were analyzed for 60 patients divided into 3 groups: MARPE (mean age 13.7 ± 1.

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Obesity is recognized as a significant risk factor for various types of cancer. Although the incidence of some types of cancer across various primary sites is decreasing due to specific prevention measures (screening programs, smoking cessation), the incidence of neoplasms in the young population shows a significant increase associated with obesity. There is sufficient evidence to say that bariatric surgery has been shown to significantly lower the risk of developing obesity-associated cancers, which are linked to metabolic dysregulation, chronic low-grade systemic inflammation, and hormonal alterations such as elevated levels of insulin and sex hormones.

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Article Synopsis
  • Ebstein's anomaly is a congenital heart condition involving tricuspid valve defects and associated complications, analyzed through data from 45 surgeries between 1990 and 2018, with a median age of 11.3 years for patients.
  • Surgical methods included valve repair (38%), cone reconstruction (42%), and replacement (19%), with additional surgeries needed for some patients, mainly for severe tricuspid insufficiency.
  • At a median follow-up of 6.5 years, the overall mortality rate was 11.5%, with favorable outcomes for cone reconstruction showing low mortality, less reoperation needed, and better medium-term durability compared to other techniques.
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Article Synopsis
  • The study aimed to assess how psychiatric disorders (PD) and weight loss change over time after Metabolic and Bariatric Surgery (MBS), analyzing data from participants up to 9 years post-surgery.
  • Conducted over nine years with 142 participants (mainly women), it found that mood and anxiety disorders increased by 32% after surgery, but the percentage of excess weight lost (%EWL) remained stable up to two years before declining slightly.
  • Despite the prevalence of psychiatric disorders after MBS, these had no significant effect on the participants’ ability to maintain weight loss, highlighting the need for ongoing support for mental health in this population.
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