Publications by authors named "M P Czech"
Article Synopsis
- - Bone health is maintained by the balance between bone formation and resorption, with osteoblasts playing a crucial role in forming new bone, a process requiring ATP and potentially impacted by systemic metabolic changes, especially in conditions like type 2 diabetes mellitus (T2DM).
- - Research shows that obese mice on a high-fat diet exhibit reduced bone quality and formation rates, correlating with increased lipid droplet accumulation in osteoblasts, which suggests that impaired lipid metabolism affects bone health.
- - A new experiment with a murine model demonstrated that deleting a specific lipid storage protein (Plin2) in osteoblasts can improve lipid breakdown and enhance bone formation, indicating that boosting fatty acid oxidation may counteract bone dysfunction caused by
Mucormycosis is an aggressive and frequently lethal disease. Most patients with mucormycosis have poorly controlled diabetes mellitus and rhino-orbito-cerebral disease. Patients with hematologic malignancy and transplant recipients mostly present with rhino-orbito-cerebral or pulmonary disease.
View Article and Find Full Text PDFIntroduction: The COVID-19 pandemic overwhelmed health systems, resulting in a surge in excess deaths. This study clustered countries based on excess mortality to understand their response to the pandemic and the influence of various factors on excess mortality within each cluster.
Materials And Methods: This ecological study is part of the COVID-19 MORtality (C-MOR) Consortium.
Objectives: Human papillomavirus (HPV) is a prevalent sexually transmitted infection with significant implications for public health. In Poland, a nationwide vaccination program offers a choice between the 9-valent (9v) and 2-valent (2v) HPV vaccines. We aimed to assess the cost-effectiveness of the 9v vs 2v vaccine from the public payer perspective in Poland.
View Article and Find Full Text PDFInfectious complications are an important cause of morbidity and mortality in patients with myelodysplastic syndromes (MDS). Preventing infections could significantly improve both survival and quality of life. Unfortunately, both infections and antimicrobial prophylaxis in patients with MDS are incompletely assessed due to the heterogeneity of disorders included in each publication, changing definitions over time, and lack of standardized prophylaxis practices.
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