Publications by authors named "M P Carver"
A role for cross-linking proteins in actin filament network organization and force generation.
Proc Natl Acad Sci U S A
October 2024
Article Synopsis
- The study explores how actin filament crosslinking proteins, particularly fimbrin, are essential for clathrin-mediated endocytosis (CME) in yeast, especially under high turgor pressure.
- Genetic experiments reveal that CME is more efficient at sites with higher concentrations of crosslinking proteins, enabling better internalization of the plasma membrane.
- Mathematical modeling supports these findings, showing that more crosslinking leads to increased force production through actin filament growth, which is vital for membrane internalization processes.
Article Synopsis
- Limited decision-support tools are available for shared decision-making (SDM) about food oral immunotherapy (OIT), prompting the creation of a new pediatric decision-aid tool covering various foods, forms, and ages.
- The tool was developed through an iterative process involving expert feedback and assessment measures, resulting in a user-friendly, 4-page aid that helps caregivers understand therapy options, risks, and benefits.
- Evaluation showed that the decision-aid was well-received by 135 caregivers, reporting high confidence in their choices and low uncertainty, indicating its effectiveness in supporting SDM for OIT initiation.
This study sought to identify COVID-19 and influenza vaccination rates and barriers among people with asthma. The Asthma and Allergy Foundation of America (AAFA) conducted an online survey from April to May in 2022 among a convenience sample of 350 individuals with asthma. Most survey respondents reported that they had received an influenza vaccine for the 2021-2022 flu season (77%) and at least 1 dose of a COVID-19 vaccine (87%).
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- The medieval period in Sicily experienced significant regime changes, transitioning from Byzantine to various Muslim rulers, and finally to Normans and Swabians, influencing local communities.
- A multidisciplinary analysis of 27 individuals from neighboring Muslim and Christian cemeteries in Segesta revealed genetic differences but also signs of continuity in diet and social practices.
- Findings indicate that both Muslim and Christian communities coexisted in the 13th century, even as regime changes led to demographic shifts and the establishment of new social relationships.
Pilot data on a pre-attending rotation for pediatric gastroenterology fellows.
J Pediatr Gastroenterol Nutr
September 2024