The tolerance of reirradiation and hyperthermia in breast cancer patients with reconstructions.

Background: Breast cancer recurrences in previously irradiated areas are treated with reirradiation (reRT) and hyperthermia (HT). The aim of this retrospective study is to quantify the toxicity of HT in breast cancer patients with reconstruction.

Methods: Between 1992 and 2009, 36 patients were treated with reRT with a scheme of 8 fractions of 4.

Reirradiation combined with hyperthermia in breast cancer recurrences: overview of experience in Erasmus MC.

For superficial hyperthermia a custom-built multi-applicator multi-amplifier superficial hyperthermia system operating at 433 MHz is utilised. Up to 6 Lucite Cone applicators can be used simultaneously to treat an area of 600 cm2. Temperatures are measured continuously with fibre optic multi-sensor probes.

Intraspinal temperatures during regional deep hyperthermia induced by electromagnetic radiation in the Macaca mulatta.

A capacitive ring system operating at 27 MHz was tested for temperature distribution in the abdominal cavity of the living Rhesus monkey. Catheters were introduced through the abdomen and their location checked after the experiment. During two of these experiments a catheter was also introduced into the intraspinal canal.

Physiological implications of hyperbaric oxygen tensions in isolated limb perfusion using melphalan: a pilot study.

Controversy exists concerning the optimal pO2 of the perfusate during isolated limb perfusion (ILP) with melphalan. Therefore we studied the implications of hyperbaric oxygen tensions in the perfusate. In 12 consecutive patients, subcutaneous pO2 (Continucath 1000), tissue and tumor pH, and blood gas values were monitored throughout the ILP procedure.

Radiofrequency capacitive heating of deep-seated tumours using pre-cooling of the subcutaneous tissues: results on thermometry in Dutch patients.

The capacity of a radiofrequency, 13.56 MHz, capacitive hyperthermia system using extensive pre-cooling of the subcutaneous tissue to induce locoregional deep heating has been investigated in 11 patients. Tumour location was presacral in nine--and eccentric towards the lateral side of the pelvis in two patients.