OSTEOPLASTIC PROPERTIES OF MULTIPOTENT MESENCHYMAL STROMAL CELLS OF ADIPOSE TISSUE.

Objective: The aim: Determining the ability of samples based on MMSC - AT differentiating in the osteogenic direction.

Patients And Methods: Materials and methods: The study was conducting at Bukovinian State Medical University, Chernivtsi, Ukraine. Adipose tissue samples were obtaining from the neck of 60 experimental animals (white Wistar rats).

[RESULTS OF BIOCHEMICAL AND HISTOLOGICAL RESEARCH IN THE RESTORATION OF BONE DEFECTS WITH THE HELP OF MULTIPOTENT MESENCHYMAL STROMAL CELLS OF ADIPOSE TISSUE].

The aim of our study was to investigate the effectiveness of osteoplastic material based on MMSC - AT for the restoration of bone defects. To study the processes of bone remodeling, in the replacement of bone defects after tooth extraction, patients were divided into three groups. Group A - 26 patients where used "Kolapan-L" to fill the bone defect; group B - 28 patients where for augmentation used osteoplastic composition "Kolopan-L" + MMSC-AT + PRP; group C - 25 patients in whom the healing of the bone defect occurred under a blood clot.