Publications by authors named "M Oota"
Background: This case report explores the long-term dynamics of insulin secretion and glycemic control in two patients with diabetes mellitus type 2 over 20 years. The observations underscore the impact of lifestyle interventions, including weight loss and calorie restriction, on insulin secretion patterns and glucose levels during 75 g oral glucose tolerance tests. Additionally, the role of hemoglobin A1c fluctuations, influenced by various factors such as body weight, exercise, and pharmacological interventions, is investigated.
View Article and Find Full Text PDFIntroduction: The soil houses a tremendous amount of micro-organisms, many of which are plant parasites and pathogens by feeding off plant roots for sustenance. Such root pathogens and parasites often rely on plant-secreted signaling molecules in the rhizosphere as host guidance cues. Here we describe the isolation and characterization of a chemoattractant of plant-parasitic root-knot nematodes (, RKN).
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- Mesenchymal stem cell transplantation is effective in treating ischemic cardiomyopathy, but the exact mechanisms behind it are unclear, prompting research into mitochondrial transfer as a potential explanation.
- In experiments with human adipose-derived stem cells and rat heart cells under low-oxygen conditions, researchers found that mitochondrial transfer enhanced energy metabolism and required direct cell contact.
- After transplanting these stem cells into a rat model with heart damage, mitochondrial transfer was observed within 3 days, leading to the presence of donor mitochondrial DNA and notable improvements in heart function.
Objectives: Cefiderocol (CFDC) is a parenteral siderophore cephalosporin that is active against Gram-negative bacteria, including carbapenem-resistant isolates. We report the in vitro activity of CFDC and other antibiotics against 1738 clinical isolates of Gram-negative bacilli (GNB) provided by five medical centres in five provinces of China in 2020 METHODS: Antibiotic susceptibility testing was performed using the Clinical and Laboratory Standards Institute broth microdilution method.
Results: Against Pseudomonas aeruginosa and Acinetobacter Spp.
Objectives: This study evaluated the sustained kill and potential for resistance development of exposed to human-simulated exposure of cefiderocol over 72 h in and infection models.
Methods: Seven isolates with cefiderocol MICs of 0.12-2 mg/L were tested.