Influence of antiplatelet medication and anticoagulation therapy after dental extractions on hospitalization: a retrospective 10-year study.

Background: The aim of this retrospective study was to identify high-risk dental extraction patients and the timing of postoperative hemorrhage to evaluate whether preventive hospitalization should be considered in patients on antiplatelet medication (AP) or anticoagulants.

Methods: Our study included 1595 procedures; 1319 were conducted under monotherapy (Group I: AP; Group II: indirect oral anticoagulant [IAC]; Group III: direct oral anticoagulant [DOAC]) and 276 under dual therapy (Group IV: double AP; Group V: AP and IAC; Group VI: AP and DOAC). We evaluated the incidence, frequency and timing of hemorrhage, hospitalization rate, and treatment of bleeding incidents.

Evaluation of the use of an advanced platelet-rich fibrin (A-PRF+) membrane in children undergoing primary palatoplasty-- a prospective randomized clinical pilot-study.

The aim of this study was to evaluate whether an A-PRF + membrane can lower the fistula rate in patients undergoing primary palatoplasty. A total of 20 children were included: 10 were randomized and included in the platelet-rich fibrin (PRF) group, and 10 were assigned to the control group. Before two-flap palatoplasty was performed, the cleft's width was measured.

Targeted radiopharmaceuticals: an underexplored strategy for ovarian cancer.

Ovarian cancer is the most common gynecological malignancy worldwide with the highest mortality. This low survival rate can be attributed to the fact that symptoms arise only at an advanced disease stage, characterized by a (micro)metastatic spread across the peritoneal cavity. Radiopharmaceuticals, composed of a targeting moiety coupled with either a diagnostic or therapeutic radionuclide, constitute a relatively underexplored theranostic approach that may improve the current standard of care.

A cadaveric study of induced isolated orbital floor fractures and implications for surgical decision-making: comparison of two preoperative imaging modalities.

Computed tomography (CT) is the gold standard for the diagnosis of isolated orbital floor fractures, while cone beam computed tomography (CBCT) is an alternative. The aim of this study was to compare the diagnostic accuracy of CT and CBCT for isolated orbital floor fractures. Forty-eight isolated orbital floor fractures were systematically induced in cadaver orbits.